Which Sakura should I keep?

So I just rolled a second Sakura and I'm going to fodder one to give my ridiculous Priscilla Fear+ and Physic+.
The one I've had forever is +def/-res which I've always thought was adequate for mixed soak, but tbh I haven't used her in months since when I do run a healer, it's almost always Priscilla.
The new one is +hp/-def, which is a big boost to her magic soak, while not losing that much physical soak, which might be better.
But Sakura's page here says def should be left neutral and a res bane is preferable. Plus, she either has a superboon or superbane in every one of her stats which makes the choice more confusing.

Thoughts?

Also pic somewhat related, Mama Priscilla almost has every healer skill in the game now :)