Definitely save.
Ishtar's strength comes from her speed, if it's neutral, then her attack can be worked around. Remember that with Mjolnir, Moonbow/Luna, 36 base speed, and Swift Sparrow, Ishtar will be doubling a majority of the roster, an atk bane will not be felt severely, I think. If it is, keep a +Atk seal on her.
I really don't think a bane like that should stop you from committing to Ishtar though, especially since she's not very expensive to build and remains a powerhouse unit in spite of that.
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