A +res/-hp spread doesn't really affect any of her more important stats, so it is really similar to a neutral spread. Atk and spd should try to be raised while def lowered, and res as well as hp don't fit any of those categories.
I would still recommend +res/-hp over a neutral one because her defensive spread still favors res over def, plus a boon is res actually boosts it by +4. Therefore potential Iceberg or Glacies can be strengthened and mages tanked better.
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