For Ninian I recommend the +Atk/-Def. For defensive purposes, she doesn’t really want to lose her speed, it does work well with TA but I think +Atk works well there too.
For Eldigan, I think the second one is also better. Although it makes him more susceptible to getting doubled, it doesn’t reduce his attack and still works great with QR. The +Spd is nice for avoiding doubles, thus making Eldigan bulkier, but the lose in his attack is quite bad.
As for Brave Lyn, I think +Res/-Def makes her better at performing in her role by gaining a very useful stat at the cost of a less useful stat, however, you can’t ever go wrong with neutral and keeping her Defence is also valuable with Cavalry buffs. So unless you need her to tank a lot of physical hits, I would go +Res/-Def. Although neutral is perfectly fine here, so I can’t give you a definite answer for her.
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