+Def/-Spd or +Att/-Res Effie?

Tough choice. Personally, I'd go with +DEF/-SPD as it's her best bane and not a bad boon. However, I think other players tend to be hyper-offensive and would prefer +ATK/-RES...relying on Wary Fighter to keep them alive long enough to get in striking range.

I'd personally go with the +ATK. It's her best boon and she can ORKO almost every unit in the game with a Brave Lance+ with a Hone Armor buff.