Nanna has significantly better survivability than Mist. High spd makes her hard to double, and her bulk is actually decently balanced to allow her to survive one hit. For most healers that's as much as can be expected without significant investment. Nanna will also be better at charging miracle because she will double any slow opponent.
However, since you've already given Mist pain+ I would just keep her. The effectiveness of pain+ compounds or snowballs as there's more of it, and dazzling staff makes Mist's low spd irrelevant during her own turn.
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