Should I sack a -HP/+DEF Minerva's LnD for my beautiful bride (lol)? She's -HP/+ATK and I don't plan to build a quad-striker and keep her weapon, also add in Threatened Speed 3 and slap a Speed seal.
P.s. Would Desperation be better on her than vantage in that case or the other way around?
Desperation is the best option for nukes with low defenses and high offenses. And I think you did the right choice with that L&D, expect good things from your Cordelia.